Ely Bridge Surgery is a very research active practice, and our patients have been taking part in studies for the past 20+ years. We participate in research studies covering a wide variety of medical conditions and have developed an excellent reputation in this field. . These studies may be sponsored by commercial or academic organisations.

As a surgery, we are committed to the conduct of high quality research relevant to the needs of our community. This gives patients the opportunity to participate in studies and allows us to progress and improve care.

The research team is led by Dr John Wakeling, supported by Dr Geraint Williams and two dedicated research nurses Sr Mel Davies and Sr Nicola Phillips.

Trials Currently in Recruitment @ Ely Bridge

The following trials are currently open to new patients. If you fit the criteria for the trial you may be contacted by telephone or post concerning these studies:


To investigate the glycaemic control in adult patients with Type 2 Diabetes who have not previously been treated with injectable glucose-lowering medication and who initiate treatment with oral Semaglutide.


The aim of this study is to investigate a possible new treatment in people with cardiovascular disease and a raised Lipoprotein(a) which is found from a blood test.

Elevated levels of Lp(a) is associated with atherosclerosis and increases the risk of Cardiovascular Disease. There are limited treatment options at present for elevated Lp(a).


The aim of this study is to create an online clinical decision support tool to help GPs find the most likely cause of male patients experiencing Lower Urinary Tract Symptoms.

This will enable the patient to get the right treatment sooner, avoid unnecessary hospital visits and expedite specialist appointments for those that need them.


Many patients with depression have symptoms that remain despite treatment with antidepressant medications.

Scientific evidence has shown a link between inflammation and depression.

This trial aims to test whether a new anti-inflammatory drug, when taken together with any current antidepressant medication can help to treat depression.


A clinical study looking at the effect of a new SDI-118 drug on cognitive function. Previous studies have shown that the drug can help improve mood. Some of these studies also suggested the drug may have positive effects on learning and memory.

The study wishes to explore whether SDI-118 may be useful in improving learning and memory difficulties that some people experience after depression.

Trials in Progress @ Ely Bridge

The following trials are currently in progress at Ely Bridge Surgery but have closed to recruitment.


A trial looking at the effect of the diabetic medication Semaglutide versus placebo on reducing the risk of cardiovascular events such as heart attack or stroke in people with established cardiovascular disease and obesity

Trial product is a once weekly pen injectable. 5 year study combining trial product and individualised health and lifestyle advice.


Trial looking at the effect of Semaglutide versus placebo on the progression of renal impairment in patients with Type 2 Diabetes and diabetic kidney disease

Trial product is a once weekly pen injectable 5 year study combining trial product and individualised health and lifestyle advice


High cholesterol is a major health concern in Europe. Appropriate medical treatment lowers a type of cholesterol called LDL and
reduces the rates of clinical cardiovascular events such as heart attacks and strokes.

This study is looking at the status of the patients health, how they are treated and the medical strategies of the Doctors.


A study looking at a new treatment for patients with chronic heart failure to assess its effects on cognitive function.

Active Brains

This study is testing an interactive programme to help people aged 60-85 with lifestyle changes and brain training activities which may help with memory and thinking skills.

It involves completing 4 online puzzle games and answering some questions about how they are when they start the study, and then again each year after that.


A study looking at how GP Surgeries could support people to take their prescribed blood pressure medications in a way that improves their health.

The Programme on Adherence to Medication (or PAM) is a new General Practice support tool that involves a text
messaging programme or a smartphone app to support medication adherance.

Trials supported by Ely Bridge


University of Bristol are currently looking for volunteers to test whether a new simple cognitive therapy in addition to taking antidepressants can be effective in helping patients with depression.